For years I’ve been hearing from parents that they suspect (or know) that their child suffered from oxygen deprivation around the time of birth, and they suspected that this contributed to their delayed development or autism diagnosis. In the past I would give remedies like Opium or Carbo Veg. However I’ve been researching Ozonum recently & will be prescribing it much more frequently going forward.

One of the most heartbreaking etiologies seen in pediatric developmental clinics is perinatal hypoxic-ischemic encephalopathy (HIE): oxygen deprivation around the time of birth that can leave a child with autism spectrum features, global developmental delay (GDD), speech apraxia, sensory processing issues, and sometimes cerebral palsy. While conventional medicine offers early intervention therapies and, in some centers, therapeutic hypothermia, many parents continue to search for additional layers of support.In the homeopathic community, a lesser-known but increasingly discussed remedy for exactly this picture is Ozonum – homeopathically prepared ozone (O₃).The proving picture of Ozonum was first sketched in 1997–1998 by a group of British homeopaths under the direction of Misha Norland and later added to by Jeremy Sherr and others. The key themes that emerged are strikingly relevant to post-hypoxic brain injury:

• Extreme exhaustion and fatigue yet restless at the same time (“tired but wired”)
• Mental dullness alternating with sudden clarity – the classic “brain fog” many of these children live in
• Sensory overload and aversion to noise/light
• Delayed speech or complete muteness in the proving (some provers temporarily lost the ability to speak)
• Hyperactivity followed by collapse
• Feeling “spaced out,” disconnected, as if in a dream
• Coldness with desire for fresh air (ozone is, after all, highly oxygenated air)
• Circulatory disturbances – cold extremities, cyanosis-like symptoms
• Affinity for the nervous system and lungs – trembling, twitching, convulsions in high potencies

Other homeopaths who work with autism and brain-injured children (Pierre Fontaine, Amy Lansky, and some of the Indian homeopaths in the “CEASE” and “Homeopathy for Autism” circles) have repeatedly noted that when the history clearly points to birth asphyxia, cord around the neck, meconium aspiration, or prolonged labor with fetal distress, Ozonum frequently appears in the repertorization and, when given in LM or centesimal potencies (usually 30C–1M), produces noticeable shifts.Common clinical observations reported anecdotally:

• Improved eye contact and social engagement within weeks
• Sudden bursts of speech or clearer articulation
• Reduction in sensory defensiveness
• Better sleep cycles
• Increased coordination and reduction in “floppiness” or spasticity

How practitioners are using it. Most are using Ozonum as part of a sequential (timeline) approach:

1. Clear vaccine or antibiotic imprints first (if indicated)
2. Address heavy metals or other toxins
3. Then give Ozonum to “re-oxygenate” the system at an energetic level, especially when the child has a history of blue-at-birth, low Apgars, NICU stay, or MRI evidence of periventricular leukomalacia (PVL).

Dosing varies widely: some give a single 200C or 1M and wait; others use daily LM/1 to LM/3 for months with remarkable gradual gains.The intriguing overlap with Hyperbaric Oxygen Therapy (HBOT)In the last decade, mild HBOT (1.3–1.5 ATA with 100% oxygen or oxygen-enriched air) has gained a dedicated following among parents of children with cerebral palsy and autism, especially when there is a documented hypoxic event at birth. Multiple small studies and one 2021 randomized trial in Thailand showed improvements in cognition, language, and social skills in post-HIE children treated with 40–60 sessions of mild HBOT.What is fascinating to homeopaths is the conceptual parallel:

• Ozone is O₃ – a super-oxygenated, highly reactive form of oxygen.
• HBOT floods the plasma and tissues with dissolved oxygen, bypassing red-blood-cell limitations.
• Both approaches are attempting, in very different paradigms, to correct the downstream effects of perinatal hypoxia on dormant or idling neurons.

Some integrative practitioners are now combining the two: using constitutional homeopathy + Ozonum while the child undergoes a course of HBOT. Parents on certain forums report the gains from HBOT seem to “stick” better when homeopathic detoxification and Ozonum are layered in. A word of caution, Ozonum is not a gentle polychrest like Phosphoric acid or Calc-carb; it is considered a “small” remedy with a very specific indication. In inexperienced hands it can produce strong aggravations (temporary increase in hyperactivity, sleep disturbance, or even seizure-like episodes). It should only be prescribed by a qualified homeopath who can take the full case and follow up closely.

Final thoughts

When a child’s developmental trajectory was derailed by lack of oxygen in those critical first minutes, the idea of using a remedy made from oxygen itself feels almost poetically appropriate. While large double-blind trials do not yet exist for Ozonum in autism/GDD (and may never exist given the nature of individualized homeopathy), the proving symptoms, clinical anecdotes from respected practitioners, and the parallel rise of HBOT are creating a growing body of experience that many parents find worth exploring under professional guidance.If your child turned blue at birth, needed resuscitation, or has MRI changes consistent with hypoxic injury, Ozonum is one remedy that deserves a place on your radar.